Review: high dose vitamin E supplementation is associated with increased all cause mortality.
نویسنده
چکیده
منابع مشابه
Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality.
BACKGROUND Experimental models and observational studies suggest that vitamin E supplementation may prevent cardiovascular disease and cancer. However, several trials of high-dosage vitamin E supplementation showed non-statistically significant increases in total mortality. PURPOSE To perform a meta-analysis of the dose-response relationship between vitamin E supplementation and total mortali...
متن کاملMeta-Regression Analyses, Meta-Analyses, and Trial Sequential Analyses of the Effects of Supplementation with Beta-Carotene, Vitamin A, and Vitamin E Singly or in Different Combinations on All-Cause Mortality: Do We Have Evidence for Lack of Harm?
BACKGROUND AND AIMS Evidence shows that antioxidant supplements may increase mortality. Our aims were to assess whether different doses of beta-carotene, vitamin A, and vitamin E affect mortality in primary and secondary prevention randomized clinical trials with low risk of bias. METHODS The present study is based on our 2012 Cochrane systematic review analyzing beneficial and harmful effect...
متن کاملVitamin E use is associated with improved survival in an Alzheimer's disease cohort.
BACKGROUND Vitamin E at a dose of 2,000 IU per day has been shown to delay Alzheimer's disease (AD) progression, but recent studies have questioned the safety of this dose level and the overall efficacy of vitamin E in AD treatment. METHODS We analyzed the survival history of 847 probable or mixed AD patients followed in a research center between 1990 and the censoring date of December 31, 20...
متن کاملSunlight Has Cardiovascular Benefits Independently of Vitamin D.
BACKGROUND High blood pressure (BP) is the leading risk factor for disability adjusted life years lost globally. Epidemiological data show a correlation between increased sun exposure and reduced population BP and cardiovascular mortality. Individuals with high serum vitamin D levels are at reduced risk of hypertension, cardiovascular disease and metabolic syndrome, yet multiple trial data show...
متن کاملEffects of Vitamin D in Neonates and Young Infants
Vitamin D is important for the development, growth, and mineralization of the skeletal in neonates and children. Vitamin D is essential for intestinal absorption of calcium. Vitamin D is metabolized to 25-hydroxyvitamin D and then to 1,25-dihydroxyvitamin D. Pregnant women in developed countries often have insufficient serum concentrations of 25-hydroxyvitamin D and a supplementation of vitamin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- ACP journal club
دوره 143 1 شماره
صفحات -
تاریخ انتشار 2005